The origins of the State Museum of History of Uzbekistan date back to 1876.
The core of the museum's collection are archaeological monuments and a collection of gold and silver coins. The artifacts come from Uzbekistan and Central Asia. The museum has, among others, an alabaster bas-relief of Buddha with Monks from Fayaz Tepe, Termez, 2nd century AD.
The museum has collected over 300,000 exhibits.